Do redheads feel more pain? Researchers at the University of Louisville in KY have found that redheads are more sensitive to heat and cold pain; a finding that the MythBusters have disputed. Who’s to say? Pain tolerance is absolutely subjective. Maybe redheads just feel pain DIFFERENTLY. There are theories that redheads feel more pain with toothaches and theories that redheads should have a HIGHER pain tolerance because of a mutation in their MC1R gene. If you ask the American Society of Anesthesiologists, they’ll tell you their research suggests redheads need MORE anesthetic than non redheads. Science Nordic found that redheads are better at eating hot peppers than the rest of us… So they should fair much better on a trip to Mexico… as long as they have a shirt and a good hat! Do Gingers Have Souls?